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The prevalence of obesity is ever increasing, especially in developed countries Increased weight (BMI 250 299) and obesity (BMI 300 ) are seen as risk factors in as many as 85% of men with ED [416] This is quite pertinent to ED because the insulin resistance that accompanies excess weight is a cause of decreased blood ow [417] The observation that insulin receptor numbers can be restored to normal if

The National Intergovernmental Audit Forum, in its handbook How to Avoid a Substandard Audit: Suggestions for Procuring an Audit, indicates:

Public entities should never select auditors without considering ve basic elements of an effective audit procurement process:

18

planning (determining what needs to be done and when), fostering competition by soliciting proposals (writing a clear and direct solicitation document and

Start with a new movie Use the Text tool to type some text In the Property inspector (Window Properties), type 100 in the Font Size text box Center the text horizontally on the Stage, so that there is an equal amount of space on the left and the right of the text It s okay if the text goes off the Stage, as long as it goes off an equal amount on either side You can eyeball this or use the Align panel (Window Align)

disseminating it widely),

.

persons to evaluate the ability of prospective auditors to effectively carry out the audit),

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preparing a written agreement (documenting the expectations of both the entity and the auditor), and monitoring the auditor s performance (periodically reviewing the progress of that performance)

ment and monitoring of late-onset hypogonadism in males ISA, ISSAM, and EAU recommendations Eur Urol 2005;48:1 4 Gennari L, Merlotti D, Martini G, Gonnelli S, Franci B, Campagna S, Lucani B, Dal Canto N, Valenti R, Gennari C, Nuti R Longitudinal association between sex hormone levels, bone loss, and bone turnover in elderly men J Clin Endocrinol Metab 2003;88:5327 5333 Rochira V, Balestrieri A, Madeo B, Spaggiari A, Carani C Congenital estrogen de ciency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men Mol Cell Endocrinol 2002;193:19 28 de Ronde W, van der Schouw YT, Pierik FH, Pols HA, Muller M, Grobbee DE, Gooren LJ, Weber RF, de Jong FH Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower levels of non-SHBG-bound testosterone in male newborns and healthy adult men Clin Endocrinol (Oxf) 2005; 62:498 503 Luboshitzky R, Shen-Orr Z, Herer P Middle-aged men secrete less testosterone at night than young healthy men J Clin Endocrinol Metab 2003;88:3160 3166 Morgentaler A, Barquawi A, O Donnel C, Lynch J, Petrylak D, Crawford ED Is it necessary to obtain a serum testosterone test in the morning Crosssectional analysis of diurnal serum testosterone variation in aging male from a large national screening program J Sex Med 2006;3(suppl 1):47, abstr 106 Bhasin S, Woodhouse L, Casaburi R, Singh AB, Bhasin D, Berman N, Chen X, Yarasheski KE, Magliano L, Dzekov C, Dzekov J, Bross R, Phillips J, Sinha-Hikim I, Shen R, Storer TW Testosterone dose-response relationships in healthy young men Am J Physiol Endocrinol Metab 2001;281:E1172 1181 Buena F, Swerdloff RS, Steiner BS, Lutchmansingh P, Peterson MA, Pandian MR, Galmarini M, Bhasin S Sexual function does not change when serum testosterone levels are pharmacologically varied within the normal male range Fertil Steril 1993;59:1118 1123 Gooren LJ Androgen levels and sex functions in testosterone-treated hypogonadal men Arch Sex Behav 1987;16:463 473 Schiavi RC, Rehman J Sexuality and aging Urol Clin North Am 1995;22:711 726 Gray PB, Singh AB, Woodhouse LJ, Storer TW, Casaburi R, Dzekov J, Dzekov C, Sinha-Hikim I, Bhasin S Dose-dependent effects of testosterone on sexual function, mood, and visuospatial cognition in older men J Clin Endocrinol Metab 2005;90: 3838 3846.

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